Open Forum Infectious Diseases
Vol. 11, Issue 3
Date of Publication:
March 2024
We determined pretreatment and acquired human immunodeficiency virus (HIV) drug resistance among children with HIV type 1 (HIV-1) in Jos, Nigeria. The majority (71%) of those who failed first-line antiretroviral therapy were on a nevirapine-containing regimen. The prevalence of pretreatment (48%) and acquired (76%) HIV drug resistance mutations was high in our study. Wider access to HIV drug resistance testing after treatment failure is necessary to optimize second-line treatment options among children with HIV in Nigeria.
Citations
Ebonyi, Augustine O., Jonathan Okpokwu, Holly Rawizza, Philippe Chebu, Beth Chaplin, Donald Hamel, Stephen Oguche, Oche O. Agbaji, Atiene S. Sagay, Phyllis J. Kanki and Godwin E. Imade. 2024. Pretreatment and Acquired Drug Resistance in Children With Human Immunodeficiency Virus Type 1 in Jos, Nigeria. Open Forum Infectious Diseases 11, no. 3 (March).